kok官网入口

吴晓倩，女，医学博士，药理学教授。广东省“特支计划”百千万人才工程青年拔尖人才、广州市首批“羊城学者”科研资助计划青年科研骨干、广东省首批广东省高等学校优秀青年教师培养计划培养对象、南山学者骨干人才。2004年—2009年在中山大学攻读硕博连读研究生获医学博士学位。分别于2006至2008年赴美国贝勒医学院医学系及2018至2020年赴美国罗彻斯特心血管疾病研究中心进修。2009年进入kok官网入口省重点学科药理学教研室至今，主要从事心血管药理学研究。目前，作为项目负责人主持国家自然科学基金2项及省市级课题多项。担任国家自然科学基金评议专家。近年来在Eur Heart J. 、Arterioscler Thromb Vasc Biol.、Pharmacol Res. 、J Mol Cell Cardiol. 、Med Res Rev. 等杂志发表SCI论文多篇，并担任Frontiers in Pharmacology等杂志审稿人。

联系邮箱：wuxiaoqian2004@hotmail.com

研究方向：自噬与心肌缺血、代谢性心肌病的发病机制及传统中药单体和小分子化合物的药物干预治疗研究

所获荣誉和奖励：

2010年获kok官网入口全英授课竞赛二等奖

2013年获广州市首批“羊城学者”科研资助计划青年科研骨干称号

2016年获广东省“特支计划”百千万人才工程青年拔尖人才称号

主要论文及著作（代表性）：

Wu X, Liu Z, Yu XY, Xu S, Luo J. Autophagy and cardiac diseases: Therapeutic potential of natural products. Med Res Rev. 2021 Jan;41(1):314-341.

Zheng D, Liu Z, Zhou Y, Hou N, Yan W, Qin Y, Ye Q, Cheng X, Xiao Q, Bao Y, Luo J, Wu X. Urolithin B, a gut microbiota metabolite, protects against myocardial ischemia/reperfusion injury via p62/Keap1/Nrf2 signaling pathway. Pharmacol Res. 2020;153:104655

Xu S, Xu Y, Liu P, Zhang S, Liu H, Slavin S, Kumar S, Koroleva M, Luo J, Wu X, Rahman A, Pelisek J, Jo H, Si S, Miller CL, Jin ZG. The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis. Eur Heart J. 2019 Aug 1;40(29):2398-2408

Wu X, Qin Y, Zhu X, Liu D, Chen F, Xu S, Zheng D, Zhou Y, Luo J. Increased expression of DRAM1 confers myocardial protection against ischemia via restoring autophagy flux. J Mol Cell Cardiol. 2018;124:70-82

Wu X, Zheng D, Qin Y, et al. Nobiletin attenuates adverse cardiac remodeling after acute myocardial infarction in rats via restoring autophagy flux. Biochem Biophys Res Commun. 2017;492(2):262–268.

Cai Y, Zhao L, Qin Y, Wu X. EGCG Blocked Phenylephrin-Induced Hypertrophy in H9C2 Cardiomyocytes, by Activating AMPK-Dependent Pathway. Korean J Physiol Pharmacol. 2015;19(3):203–210.

Wu X, He L, Chen F, et al. Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction. PLoS One. 2014;9(11):e112891.

Wu X, He L, Cai Y, et al. Induction of autophagy contributes to the myocardial protection of valsartan against ischemiareperfusion injury. Mol Med Rep. 2013;8(6):1824–1830.

Wang P^#, Wu X^#, Bao YX, Fang J, Zhou SG, Gao J, Pi R, Mou YG, Liu PQ. Tanshinone IIA prevents cardiac remodeling through attenuating NAD (P)H oxidase- derived reactive oxygen species production in hypertensive rats. Pharmazie 2011;66(7):517-24.

Wu X, Cheng J, Li P, et al. Mechano-sensitive transcriptional factor Egr-1 regulates insulin-like growth factor-1 receptor expression and contributes to neointima formation in vein grafts. Arterioscler Thromb Vasc Biol. 2010;30(3):471–476.

Wu X, Huang HQ, Tang FT, Le K, Xu SW, Liu PQ. Regulated expression of endothelial lipase in atherosclerosis. Mol Cell Endocrinol. 2010; 315(1-2):233-8.